FILE - Colorado head coach Deion Sanders, left, talks with quarterback Shedeur Sanders (2) during a timeout in the second half of an NCAA college football game against Central Florida, Saturday, Sept. 28, 2024, in Orlando, Fla. AP They don’t want to lose their Week 18 game against the Eagles. They don’t care about the draft implications.

While some teams still try to make the playoffs, several NFL franchises could change their fortunes with a loss in Week 18, with the right to earn the No. 1 overall pick in the 2025 NFL Draft still up for grabs.

The Giants' odds of securing the No. 1 overall pick are slim, but they still have a great chance of landing a pick inside the top three.

In our latest NFL mock draft from Christian D’Andrea, he had the Giants taking Miami’s Cam Ward, who just played half of the Pop-Tarts Bowl. But in the latest 2025 mock from CBS Sports, Josh Edwards has Big Blue sitting at No. 4 and taking Colorado’s Shedeur Sanders. Here’s his take:

The Giants’ search for their future quarterback was complicated Sunday by beating the Colts and slipping in the projected draft order.

After an unlikely Week 17 victory, the New York Giants are now slated to selected fourth overall in the 2025 NFL draft.

The Giants' win over the Colts puts New York further back in the order for the 2025 NFL draft for now, but players and coaches reveled in the outcome.

Thanks to their win over the Indianapolis Colts, combined with the losses by New England, Tennessee, and Cleveland, the Giants slipped from first to fourth in the 2025 draft order.

The New England Patriots, who are currently slated to pick first overall in the 2025 NFL draft, find themselves at a pivotal moment. They’ll have a chance to secure a franchise-altering draft haul if they lose to the Buffalo Bills in Week 18.

Four teams enter Week 18 tied for the worst record in the NFL. Here's how each of them could get the No. 1 pick in the 2025 NFL Draft.