The San Francisco 49ers may be unable to avoid losing one of their defensive superstars, but seeing him land with a division ...

The New England Patriots lost their third consecutive game Sunday in a Week 4 loss to the San Francisco 49ers on the road, ...

San Francisco 49ers quarterback Brock Purdy made NFL history following the team's win over the Patriots on Sunday.

San Francisco 49ers tight end George Kittle received high praise from Vernon Davis. The former NFL player believes he sees much of himself in Kittle.

Check out our NFL Week 5 picks and NFL Week 5 predictions for the 14 NFL games this week. The Falcons won their game with a ...

San Francisco 49ers quarterback Brock Purdy has started 25 regular-season games in his career, boasting a 19-6 record. Leading the NFL with 1,130 ...

NFL players always say that they don't pay much attention to media. However, it is usually clear when they actually are ...

Looking at Sunday’s Arizona Cardinals at San Francisco 49ers Week 5 NFL odds, lines and trends. Here’s what you need to know.

Tom Pelissero of the NFL Network is reporting that Miami Dolphins running back Raheem Mostert will not play vs the Titans on ...

Sunday's loss comes after the Patriots' second-half implosion against the Seahawks and a hapless Thursday night performance ...

Wide receiver Mike Evans on becoming the Tampa Bay Buccaneers all-time leading scorer.

NFL Week 5 betting spreads, lines, point totals for every game on the Week 5 NFL schedule, with odds for favorites and underdogs in each NFL matchup.