Looking at Sunday’s San Francisco 49ers at Green Bay Packers Week 12 NFL odds, lines and trends. Here’s what you need to know.

The 34-year-old quarterback runs and throws Seattle to its 1st win over San Francisco in 7 tries, back into NFC West race.

The Packers got back to winning ways in Week 11 and host a 49ers side who are suffering their own difficulties this season. ...

The Arizona Cardinals (6-4) are on the road in Week 12 to face the Seattle Seahawks (5-5) for an important NFC West matchup.

The Bengals have been waiting for a turnaround that might never come, as Cincinnati could be in too deep of a hole to mount a playoff push.

Should Kansas City Chiefs, Buffalo Bills or Detroit Lions be ranked No. 1 now? For first time this season, there's debate.

The change from Shane Waldron to Thomas Brown at offensive coordinator nevertheless yielded benefits for the home team; ...

From the Steelers pushing back the Ravens to the Bills spoiling the Chiefs' perfect run, sparks flew in heated rivalries ...

Nick Bosa’s injury definitely hurt the 49ers in loss to Seahawks and there’s concern he could miss additional time.

The Panthers have had three different starting centers in their first 10 games of the season. None of those centers had ...

The Seattle Seahawks (5-5) and Arizona Cardinals (6-4) are set to meet at Lumen Field on Nov. 24, which means that Geno Smith ...

There is no Steve Wilks to blame. There is no bye week to get things right. And now the focus is starting to shift to ...